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A Novel High-Throughput Vaccinia Virus Neutralization Assay and Preexisting Immunity in Populations from Different Geographic Regions in China

BACKGROUND: Pre-existing immunity to Vaccinia Tian Tan virus (VTT) resulting from a large vaccination campaign against smallpox prior to the early 1980s in China, has been a major issue for application of VTT-vector based vaccines. It is essential to establish a sensitive and high-throughput neutral...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Huang, Weijin, Nie, Jianhui, Zhu, Rong, Gao, Dongying, Song, Aijing, Meng, Shufang, Xu, Xuemei, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306400/
https://www.ncbi.nlm.nih.gov/pubmed/22438922
http://dx.doi.org/10.1371/journal.pone.0033392