Anthrax Lethal Toxin Disrupts Intestinal Barrier Function and Causes Systemic Infections with Enteric Bacteria

A variety of intestinal pathogens have virulence factors that target mitogen activated protein kinase (MAPK) signaling pathways, including Bacillus anthracis. Anthrax lethal toxin (LT) has specific proteolytic activity against the upstream regulators of MAPKs, the MAPK kinases (MKKs). Using a murine...

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Detalles Bibliográficos
Autores principales: Sun, Chen, Fang, Hui, Xie, Tao, Auth, Roger D., Patel, Nayana, Murray, Patrick R., Snoy, Philip J., Frucht, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306423/
https://www.ncbi.nlm.nih.gov/pubmed/22438953
http://dx.doi.org/10.1371/journal.pone.0033583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306423/
https://www.ncbi.nlm.nih.gov/pubmed/22438953
http://dx.doi.org/10.1371/journal.pone.0033583

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