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Down-Regulation of Glucose-Regulated Protein (GRP) 78 Potentiates Cytotoxic Effect of Celecoxib in Human Urothelial Carcinoma Cells

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that has been reported to elicit anti-proliferative response in various tumors. In this study, we aim to investigate the antitumor effect of celecoxib on urothelial carcinoma (UC) cells and the role endoplasmic reticulum (ER) stress plays i...

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Detalles Bibliográficos
Autores principales: Huang, Kuo-How, Kuo, Kuan-Lin, Chen, Shyh-Chyan, Weng, Te-I, Chuang, Yuan-Ting, Tsai, Yu-Chieh, Pu, Yeong-Shiau, Chiang, Chih-Kang, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306428/
https://www.ncbi.nlm.nih.gov/pubmed/22438966
http://dx.doi.org/10.1371/journal.pone.0033615