Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cancer cells are metabolically stressed during tumour progression due to limited tumour vascularity and resultant nutrient, growth factor and oxygen deficiency that can induce cell death and inhibit tumour growth. We demonstrate that Rab25, a small GTPase involved in endosomal recycling, that is gen...

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Detalles Bibliográficos
Autores principales: Cheng, Kwai Wa, Agarwal, Roshan, Mitra, Shreya, Lee, Ju-Seog, Carey, Mark, Gray, Joe W, Mills, Gordon B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306554/
https://www.ncbi.nlm.nih.gov/pubmed/22253197
http://dx.doi.org/10.1002/emmm.201100193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306554/
https://www.ncbi.nlm.nih.gov/pubmed/22253197
http://dx.doi.org/10.1002/emmm.201100193

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