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Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress
Cancer cells are metabolically stressed during tumour progression due to limited tumour vascularity and resultant nutrient, growth factor and oxygen deficiency that can induce cell death and inhibit tumour growth. We demonstrate that Rab25, a small GTPase involved in endosomal recycling, that is gen...
Autores principales: | Cheng, Kwai Wa, Agarwal, Roshan, Mitra, Shreya, Lee, Ju-Seog, Carey, Mark, Gray, Joe W, Mills, Gordon B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306554/ https://www.ncbi.nlm.nih.gov/pubmed/22253197 http://dx.doi.org/10.1002/emmm.201100193 |
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