Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation

Epithelial myosin light chain kinase (MLCK)-dependent barrier dysfunction contributes to the pathogenesis of inflammatory bowel diseases (IBD). We reported that epithelial GM-CSF–STAT5 signalling is essential for intestinal homeostatic response to gut injury. However, mechanism, redundancy by STAT5...

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Detalles Bibliográficos
Autores principales: Gilbert, Shila, Zhang, Rongli, Denson, Lee, Moriggl, Richard, Steinbrecher, Kris, Shroyer, Noah, Lin, James, Han, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306555/
https://www.ncbi.nlm.nih.gov/pubmed/22228679
http://dx.doi.org/10.1002/emmm.201100192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306555/
https://www.ncbi.nlm.nih.gov/pubmed/22228679
http://dx.doi.org/10.1002/emmm.201100192

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