N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

Wnt signalling has pivotal roles in tumour progression and metastasis; however, the exact molecular mechanism of Wnt signalling in the metastatic process is as yet poorly defined. Here we demonstrate that the tumour metastasis suppressor gene, NDRG1, interacts with the Wnt receptor, LRP6, followed b...

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Detalles Bibliográficos
Autores principales: Liu, Wen, Xing, Fei, Iiizumi-Gairani, Megumi, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Kobayashi, Aya, Mo, Yin-Yuan, Fukuda, Koji, Li, Yi, Watabe, Kounosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306556/
https://www.ncbi.nlm.nih.gov/pubmed/22246988
http://dx.doi.org/10.1002/emmm.201100190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306556/
https://www.ncbi.nlm.nih.gov/pubmed/22246988
http://dx.doi.org/10.1002/emmm.201100190

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