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N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis
Wnt signalling has pivotal roles in tumour progression and metastasis; however, the exact molecular mechanism of Wnt signalling in the metastatic process is as yet poorly defined. Here we demonstrate that the tumour metastasis suppressor gene, NDRG1, interacts with the Wnt receptor, LRP6, followed b...
Autores principales: | Liu, Wen, Xing, Fei, Iiizumi-Gairani, Megumi, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Kobayashi, Aya, Mo, Yin-Yuan, Fukuda, Koji, Li, Yi, Watabe, Kounosuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306556/ https://www.ncbi.nlm.nih.gov/pubmed/22246988 http://dx.doi.org/10.1002/emmm.201100190 |
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