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Multivariate analysis of immunohistochemical evaluation of protein expression in pancreatic ductal adenocarcinoma reveals prognostic significance for persistent Smad4 expression only

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with a 5-year survival rate of <5% and an average survival of only 6 months. Although advances have been made in understanding the pathogenesis of PDAC in the last decades, overall survival has not changed. Various clinico...

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Detalles Bibliográficos
Autores principales: Ottenhof, Niki A., Morsink, Folkert H. M., ten Kate, Fiebo, van Noorden, Cornelis J. F., Offerhaus, G. Johan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306569/
https://www.ncbi.nlm.nih.gov/pubmed/22351431
http://dx.doi.org/10.1007/s13402-012-0072-x