Cargando…

Multivariate analysis of immunohistochemical evaluation of protein expression in pancreatic ductal adenocarcinoma reveals prognostic significance for persistent Smad4 expression only

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with a 5-year survival rate of <5% and an average survival of only 6 months. Although advances have been made in understanding the pathogenesis of PDAC in the last decades, overall survival has not changed. Various clinico...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ottenhof, Niki A., Morsink, Folkert H. M., ten Kate, Fiebo, van Noorden, Cornelis J. F., Offerhaus, G. Johan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306569/ https://www.ncbi.nlm.nih.gov/pubmed/22351431 http://dx.doi.org/10.1007/s13402-012-0072-x

Ejemplares similares

Molecular Characteristics of Pancreatic Ductal Adenocarcinoma
por: Ottenhof, Niki A., et al.
Publicado: (2011)

Expression of cyclooxygenase-2 and mucin 1 in colorectal cancer
por: Szlendak, Małgorzata, et al.
Publicado: (2020)

Stem cell dynamics and pretumor progression in the intestinal tract
por: Ma, Huiying, et al.
Publicado: (2016)

Assessment of ARX expression, a novel biomarker for metastatic risk in pancreatic neuroendocrine tumors, in endoscopic ultrasound fine‐needle aspiration
por: Hackeng, Wenzel M., et al.
Publicado: (2019)

Low frequency of HER2 amplification and overexpression in early onset gastric cancer
por: Moelans, Cathy B., et al.
Publicado: (2011)

Expression pattern of p-Smad2/Smad4 as a predictor of survival in invasive breast ductal carcinoma
por: Liu, Nannan, et al.
Publicado: (2020)

Immunohistochemical Expression of Nanog and Its Relation with Clinicopathologic Characteristics in Breast Ductal Carcinoma
por: Saravi, Omid Emadian, et al.
Publicado: (2019)

Immunohistochemical Evaluation of the Expression of Specific Membrane Antigens in Patients with Pancreatic Ductal Adenocarcinoma
por: Nicoletti, Alberto, et al.
Publicado: (2023)

Validation of tissue microarray technology in squamous cell carcinoma of the esophagus
por: Boone, Judith, et al.
Publicado: (2008)

High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype
por: Machlowska, Julita, et al.
Publicado: (2020)

Status of CHEK2 and p53 in patients with early-onset and conventional gastric cancer
por: Machlowska, Julita, et al.
Publicado: (2021)

Comparison of Syndecan-1 Immunohistochemical Expression in Lobular and Ductal Breast Carcinoma with Nodal Metastases
por: Miše, Ivana, et al.
Publicado: (2018)

Immunohistochemical categorisation of ductal carcinoma in situ of the breast
por: Meijnen, P, et al.
Publicado: (2008)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

Detecting multivariate differentially expressed genes
por: Nilsson, Roland, et al.
Publicado: (2007)

Ductal adenocarcinoma of the prostate: immunohistochemical findings and clinical significance
por: Sha, Jianjun, et al.
Publicado: (2013)

Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas
por: Hackeng, Wenzel M., et al.
Publicado: (2020)

Expression of TNF-superfamily members BAFF and APRIL in breast cancer: Immunohistochemical study in 52 invasive ductal breast carcinomas
por: Pelekanou, Vassiliki, et al.
Publicado: (2008)

Immunohistochemical profile of high-grade ductal carcinoma in situ of the breast
por: Perez, Amanda Arantes, et al.
Publicado: (2013)

COVID-19 does not only disturb our social rhythm
por: Wilde, Arthur A.M., et al.
Publicado: (2021)

SMAD4 and the TGFβ Pathway in Patients with Pancreatic Ductal Adenocarcinoma
por: Dardare, Julie, et al.
Publicado: (2020)

An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma
por: Houvast, Ruben D., et al.
Publicado: (2021)

A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival
por: Singh, Puneet, et al.
Publicado: (2011)

Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review
por: Kryklyva, Valentyna, et al.
Publicado: (2019)

Immunohistochemical evaluation of phosphorylated SMAD2/SMAD3 and the co-activator P300 in human glomerulonephritis: correlation with renal injury
por: Kassimatis, Theodoros I, et al.
Publicado: (2006)

Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis
por: Block, Mattias, et al.
Publicado: (2016)

Immunohistochemical expression of SMAD4, CK19, and CA19-9 in fine needle aspiration samples of pancreatic adenocarcinoma: Utility and potential role
por: Zapata, Mauricio, et al.
Publicado: (2007)

Prognostic Implication of pAMPK Immunohistochemical Staining by Subcellular Location and Its Association with SMAD Protein Expression in Clear Cell Renal Cell Carcinoma
por: Jung, Minsun, et al.
Publicado: (2019)

Expression of e-cadherin, n-cadherin and snail and their correlation with clinicopathological variants: an immunohistochemical study of 132 invasive ductal breast carcinomas in Egypt
por: ElMoneim, Hanan Mohamed Abd, et al.
Publicado: (2011)

Smad1 Expression in Follicular Lymphoma
por: Go, Jai Hyang
Publicado: (2015)

SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
por: Chen, Yu-Wen, et al.
Publicado: (2014)

Expression of p53 and PTEN in human primary endometrial carcinomas: Clinicopathological and immunohistochemical analysis and study of their concomitant expression
por: Stavropoulos, Aggelis, et al.
Publicado: (2019)

Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma
por: Penheiter, Alan R., et al.
Publicado: (2015)

A Morphological and Immunohistochemical Study of the Tumoral and Inflammatory Cells in Pancreatic Ductal Adenocarcinoma
por: Herlea, Vlad, et al.
Publicado: (2020)

Are Bacterial Persisters Dormant Cells Only?
por: Zou, Jin, et al.
Publicado: (2022)

Understanding Pancreatic Ductal Morphogenesis and Function: Gene Deletion Is Only the Beginning
por: Williams, John A.
Publicado: (2015)

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma
por: Chen, Ru, et al.
Publicado: (2014)

Expression and Polymorphisms of SMAD1, SMAD2 and SMAD3 Genes and Their Association with Litter Size in Tibetan Sheep (Ovis aries)
por: Li, Mingming, et al.
Publicado: (2022)

Immunohistochemical expression of insulin-like growth factor binding protein-3 in invasive breast cancers and ductal carcinoma in situ: implications for clinicopathology and patient outcome
por: Vestey, Sarah B, et al.
Publicado: (2005)

Study of Estrogen Receptor and Progesterone Receptor Expression in Breast Ductal Carcinoma In Situ by Immunohistochemical Staining in ER/PgR-Negative Invasive Breast Cancer
por: Dobrescu, Andrei, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ofjvnnv4v01ivrgvckq7v5md4l