Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency

BACKGROUND: The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have demonstrated significant associations with SNPs in the chromosome 15q region that i...

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Detalles Bibliográficos
Autores principales: Kim, Woo Jin, Wood, Alice M, Barker, Alan F, Brantly, Mark L, Campbell, Edward J, Eden, Edward, McElvaney, Gerard, Rennard, Stephen I, Sandhaus, Robert A, Stocks, James M, Stoller, James K, Strange, Charlie, Turino, Gerard, Silverman, Edwin K, Stockley, Robert A, DeMeo, Dawn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306733/
https://www.ncbi.nlm.nih.gov/pubmed/22356581
http://dx.doi.org/10.1186/1465-9921-13-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306733/
https://www.ncbi.nlm.nih.gov/pubmed/22356581
http://dx.doi.org/10.1186/1465-9921-13-16

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