Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma

Sonic hedgehog (Shh) signaling is critical during development and its aberration is common across the spectrum of human malignancies. In the cerebellum, excessive activity of the Shh signaling pathway is associated with the devastating pediatric brain tumor medulloblastoma. We previously demonstrate...

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Detalles Bibliográficos
Autores principales: Bhatia, Bobby, Potts, Chad R., Guldal, Cemile, Choi, SunPhil, Korshunov, Andrey, Pfister, Stefan, Kenney, Anna M., Nahlé, Zaher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306783/
https://www.ncbi.nlm.nih.gov/pubmed/22407012
http://dx.doi.org/10.1007/s00401-012-0968-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306783/
https://www.ncbi.nlm.nih.gov/pubmed/22407012
http://dx.doi.org/10.1007/s00401-012-0968-6

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