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PED/PEA-15 Controls Fibroblast Motility and Wound Closure by ERK1/2-Dependent Mechanisms

Cell migration is dependent on the control of signaling events that play significant roles in creating contractile force and in contributing to wound closure. We evaluated wound closure in fibroblasts from mice overexpressing (TgPED) or lacking ped/pea-15 (KO), a gene overexpressed in patients with...

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Detalles Bibliográficos
Autores principales: Buonomo, Roberta, Giacco, Ferdinando, Vasaturo, Angela, Caserta, Sergio, Guido, Stefano, Pagliara, Valentina, Garbi, Corrado, Mansueto, Gelsomina, Cassese, Angela, Perruolo, Giuseppe, Oriente, Francesco, Miele, Claudia, Beguinot, Francesco, Formisano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306794/
https://www.ncbi.nlm.nih.gov/pubmed/21780113
http://dx.doi.org/10.1002/jcp.22944