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A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations

Genome-wide association studies (GWAS) have become the preferred experimental design in exploring the genetic etiology of complex human traits and diseases. Standard SNP-based meta-analytic approaches have been utilized to integrate the results from multiple experiments. This fundamentally assumes t...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Liu, Xuanyao, Sim, Xueling, Xu, Haiyan, Khor, Chiea-Chuen, Ong, Rick Twee-Hee, Tay, Wan-Ting, Suo, Chen, Poh, Wan-Ting, Ng, Daniel Peng-Keat, Liu, Jianjun, Aung, Tin, Chia, Kee-Seng, Wong, Tien-Yin, Tai, E-Shyong, Teo, Yik-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306862/
https://www.ncbi.nlm.nih.gov/pubmed/22126751
http://dx.doi.org/10.1038/ejhg.2011.219