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Diverse Roles of JNK and MKK Pathways in the Brain

The c-Jun NH(2)-terminal protein kinase (JNK) plays important roles in a broad range of physiological processes. JNK is controlled by two upstream regulators, mitogen-activated protein kinase kinase (MKK) 4 and MKK7, which are activated by various MAPKKKs. Studies employing knockout mice have demons...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tokiwa, Kawasaki, Hiroshi, Nishina, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307000/
https://www.ncbi.nlm.nih.gov/pubmed/22496975
http://dx.doi.org/10.1155/2012/459265