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The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues

BACKGROUND: Pro-inflammatory cytokines possess osteoclastogenic or anti-osteoclastogenic activities. They influence osteoclasts directly or via the receptor activator of nuclear factor κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG) system. Recent evidence suggests that inflammation may pla...

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Detalles Bibliográficos
Autores principales: Zupan, Janja, Komadina, Radko, Marc, Janja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307025/
https://www.ncbi.nlm.nih.gov/pubmed/22380539
http://dx.doi.org/10.1186/1423-0127-19-28