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The export factor Yra1 modulates mRNA 3’ end processing

The yeast mRNA export adaptor Yra1 binds the Pcf11 subunit of cleavage-polyadenylation factor CF1A linking export to 3’-end formation. We found a surprising consequence of this interaction is that Yra1 influences cleavage-polyadenylation. Yra1 competes with the CF1A subunit, Clp1, for binding to Pcf...

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Detalles Bibliográficos
Autores principales: Johnson, Sara A., Kim, Hyunmin, Erickson, Benjamin, Bentley, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307051/
https://www.ncbi.nlm.nih.gov/pubmed/21947206
http://dx.doi.org/10.1038/nsmb.2126