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A method to infer positive selection from marker dynamics in an asexual population

Motivation: The observation of positive selection acting on a mutant indicates that the corresponding mutation has some form of functional relevance. Determining the fitness effects of mutations thus has relevance to many interesting biological questions. One means of identifying beneficial mutation...

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Detalles Bibliográficos
Autores principales: Illingworth, Christopher J. R., Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307107/
https://www.ncbi.nlm.nih.gov/pubmed/22223745
http://dx.doi.org/10.1093/bioinformatics/btr722