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A method to infer positive selection from marker dynamics in an asexual population
Motivation: The observation of positive selection acting on a mutant indicates that the corresponding mutation has some form of functional relevance. Determining the fitness effects of mutations thus has relevance to many interesting biological questions. One means of identifying beneficial mutation...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307107/ https://www.ncbi.nlm.nih.gov/pubmed/22223745 http://dx.doi.org/10.1093/bioinformatics/btr722 |