In Channelrhodopsin-2 Glu-90 Is Crucial for Ion Selectivity and Is Deprotonated during the Photocycle

The light-activated microbial ion channel channelrhodopsin-2 (ChR2) is a powerful tool to study cellular processes with high spatiotemporal resolution in the emerging field of optogenetics. To customize the channel properties for optogenetic experiments, a detailed understanding of its molecular rea...

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Detalles Bibliográficos
Autores principales: Eisenhauer, Kirstin, Kuhne, Jens, Ritter, Eglof, Berndt, André, Wolf, Steffen, Freier, Erik, Bartl, Franz, Hegemann, Peter, Gerwert, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307317/
https://www.ncbi.nlm.nih.gov/pubmed/22219197
http://dx.doi.org/10.1074/jbc.M111.327700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307317/
https://www.ncbi.nlm.nih.gov/pubmed/22219197
http://dx.doi.org/10.1074/jbc.M111.327700

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