Glutathione S-Transferase Omega 1 Activity Is Sufficient to Suppress Neurodegeneration in a Drosophila Model of Parkinson Disease

A loss-of-function mutation in the gene parkin causes a common neurodegenerative disease that may be caused by mitochondrial dysfunction. Glutathione S-transferase Omega (GSTO) is involved in cell defense mechanisms, but little is known about the role of GSTO in the progression of Parkinson disease....

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Detalles Bibliográficos
Autores principales: Kim, Kiyoung, Kim, Song-Hee, Kim, Jaekwang, Kim, Heuijong, Yim, Jeongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307323/
https://www.ncbi.nlm.nih.gov/pubmed/22219196
http://dx.doi.org/10.1074/jbc.M111.291179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307323/
https://www.ncbi.nlm.nih.gov/pubmed/22219196
http://dx.doi.org/10.1074/jbc.M111.291179

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