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Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE(−/−) mice

AIMS: Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. However, it remains unclear whether a primary increase in superoxide production specifically in the endothelium alters the initiation or progress...

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Detalles Bibliográficos
Autores principales: Douglas, Gillian, Bendall, Jennifer K., Crabtree, Mark J., Tatham, Amy L., Carter, Emma E., Hale, Ashley B., Channon, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307381/
https://www.ncbi.nlm.nih.gov/pubmed/22287576
http://dx.doi.org/10.1093/cvr/cvs026