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Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE(−/−) mice
AIMS: Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. However, it remains unclear whether a primary increase in superoxide production specifically in the endothelium alters the initiation or progress...
Autores principales: | Douglas, Gillian, Bendall, Jennifer K., Crabtree, Mark J., Tatham, Amy L., Carter, Emma E., Hale, Ashley B., Channon, Keith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307381/ https://www.ncbi.nlm.nih.gov/pubmed/22287576 http://dx.doi.org/10.1093/cvr/cvs026 |
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