miR-181a Post-Transcriptionally Downregulates Oncogenic RalA and Contributes to Growth Inhibition and Apoptosis in Chronic Myelogenous Leukemia (CML)

MicroRNAs (miRNAs) are a class of short RNAs that regulate gene expression through either translational repression or mRNA cleavage. miRNA-181a (miR-181a), one of the many miRNAs conserved among vertebrates, is differentially expressed in a variety of leukemia. However, its function in leukemia, par...

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Detalles Bibliográficos
Autores principales: Fei, Jia, Li, Yumin, Zhu, Xuejiao, Luo, Xiaochuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307705/
https://www.ncbi.nlm.nih.gov/pubmed/22442671
http://dx.doi.org/10.1371/journal.pone.0032834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307705/
https://www.ncbi.nlm.nih.gov/pubmed/22442671
http://dx.doi.org/10.1371/journal.pone.0032834

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