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N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity

The activation of group I metabotropic glutamate receptor (group I mGlus) has been shown to produce neuroprotective or neurotoxic effects. In this study, we investigated the effects of N-acetylcysteine (NAC), a precursor of the antioxidant glutathione, on group I mGlus activation in apoptosis of gli...

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Detalles Bibliográficos
Autores principales: Sun, Lili, Gu, Li, Wang, Shuting, Yuan, Jifang, Yang, Huimin, Zhu, Jiawei, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307713/
https://www.ncbi.nlm.nih.gov/pubmed/22442667
http://dx.doi.org/10.1371/journal.pone.0032503