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Ablation of the Pro-Apoptotic Protein Bax Protects Mice from Glucocorticoid-Induced Bone Growth Impairment

Dexamethasone (Dexa) is a widely used glucocorticoid to treat inflammatory diseases; however, a multitude of undesired effects have been reported to arise from this treatment including osteoporosis, obesity, and in children decreased longitudinal bone growth. We and others have previously shown that...

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Detalles Bibliográficos
Autores principales: Zaman, Farasat, Chrysis, Dionisios, Huntjens, Kirsten, Fadeel, Bengt, Sävendahl, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307731/
https://www.ncbi.nlm.nih.gov/pubmed/22442678
http://dx.doi.org/10.1371/journal.pone.0033168