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Surface Plasmon Resonance Reveals a Different Pattern of Proinsulin Autoantibodies Concentration and Affinity in Diabetic Patients

Type 1 diabetes mellitus (DM) is characterized by autoimmune aggression against pancreatic beta cells resulting in absolute deficiency of insulin secretion. The first detectable sign of emerging autoimmunity during the preclinical asymptomatic period is the appearance of diabetes-related autoantibod...

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Detalles Bibliográficos
Autores principales: Trabucchi, Aldana, Guerra, Luciano L., Faccinetti, Natalia I., Iacono, Rubén F., Poskus, Edgardo, Valdez, Silvina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307739/
https://www.ncbi.nlm.nih.gov/pubmed/22442700
http://dx.doi.org/10.1371/journal.pone.0033574