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Surface Plasmon Resonance Reveals a Different Pattern of Proinsulin Autoantibodies Concentration and Affinity in Diabetic Patients
Type 1 diabetes mellitus (DM) is characterized by autoimmune aggression against pancreatic beta cells resulting in absolute deficiency of insulin secretion. The first detectable sign of emerging autoimmunity during the preclinical asymptomatic period is the appearance of diabetes-related autoantibod...
Autores principales: | Trabucchi, Aldana, Guerra, Luciano L., Faccinetti, Natalia I., Iacono, Rubén F., Poskus, Edgardo, Valdez, Silvina N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307739/ https://www.ncbi.nlm.nih.gov/pubmed/22442700 http://dx.doi.org/10.1371/journal.pone.0033574 |
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