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Neonatal Colonisation Expands a Specific Intestinal Antigen-Presenting Cell Subset Prior to CD4 T-Cell Expansion, without Altering T-Cell Repertoire

Interactions between the early-life colonising intestinal microbiota and the developing immune system are critical in determining the nature of immune responses in later life. Studies in neonatal animals in which this interaction can be examined are central to understanding the mechanisms by which t...

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Detalles Bibliográficos
Autores principales: Inman, Charlotte F., Laycock, Georgina M., Mitchard, Louisa, Harley, Ross, Warwick, James, Burt, Rachel, van Diemen, Pauline M., Stevens, Mark, Bailey, Mick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307746/
https://www.ncbi.nlm.nih.gov/pubmed/22442714
http://dx.doi.org/10.1371/journal.pone.0033707