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Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation

BACKGROUND: FAAH (fatty acid amide hydrolase), primarily expressed in the liver, hydrolyzes the endocannabinoids fatty acid ethanolamides (FAA). Human FAAH gene mutations are associated with increased body weight and obesity. In our present study, using targeted metabolite and lipid profiling, and n...

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Detalles Bibliográficos
Autores principales: Vaitheesvaran, Bhavapriya, Yang, Li, Hartil, Kirsten, Glaser, Sherrye, Yazulla, Stephen, Bruce, James E., Kurland, Irwin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307749/
https://www.ncbi.nlm.nih.gov/pubmed/22442717
http://dx.doi.org/10.1371/journal.pone.0033717