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A Deadenylase Assay by Size-Exclusion Chromatography

The shortening of the 3′-end poly(A) tail, also called deadenylation, is crucial to the regulation of mRNA processing, transportation, translation and degradation. The deadenylation process is achieved by deadenylases, which specifically catalyze the removal of the poly(A) tail at the 3′-end of euka...

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Detalles Bibliográficos
Autores principales: He, Guang-Jun, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307757/
https://www.ncbi.nlm.nih.gov/pubmed/22442711
http://dx.doi.org/10.1371/journal.pone.0033700