Titin and diaphragm dysfunction in mechanically ventilated rats

PURPOSE: Diaphragm weakness induced by mechanical ventilation may contribute to difficult weaning from the ventilator. For optimal force generation the muscle proteins myosin and titin are indispensable. The present study investigated if myosin and titin loss or dysfunction are involved in mechanica...

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Detalles Bibliográficos
Autores principales: van Hees, Hieronymus W. H., Schellekens, Willem-Jan M., Andrade Acuña, Gilberto L., Linkels, Marianne, Hafmans, Theo, Ottenheijm, Coen A. C., Granzier, Henk L., Scheffer, Gert-Jan, van der Hoeven, Johannes G., Dekhuijzen, P. N. Richard, Heunks, Leo M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Experimental
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308006/
https://www.ncbi.nlm.nih.gov/pubmed/22327561
http://dx.doi.org/10.1007/s00134-012-2504-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308006/
https://www.ncbi.nlm.nih.gov/pubmed/22327561
http://dx.doi.org/10.1007/s00134-012-2504-5

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