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HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients

INTRODUCTION: The revised shared epitope (SE) concept in rheumatoid arthritis (RA) is based on the presence (S) or absence (X) of the SE RAA amino acid motif at positions 72 to 74 of the third hypervariable region of the various human leucocyte antigen (HLA)-DRB1 alleles. The purpose of this study w...

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Detalles Bibliográficos
Autores principales: Meyer, Pieter WA, Hodkinson, Bridget, Ally, Mahmood, Musenge, Eustasius, Wadee, Ahmed A, Fickl, Heidi, Tikly, Mohammed, Anderson, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308093/
https://www.ncbi.nlm.nih.gov/pubmed/21978430
http://dx.doi.org/10.1186/ar3479