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The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus
The focus of the present review is on the extent to which epigenetic alterations influence the development of systemic lupus erythematosus. Lupus is a systemic autoimmune disease characterized by the production of autoantibodies directed at nuclear self-antigens. A DNA methylation defect in CD4+ T c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308098/ https://www.ncbi.nlm.nih.gov/pubmed/22044622 http://dx.doi.org/10.1186/ar3484 |