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Role of major histocompatibility complex class II in the development of autoimmune type 1 diabetes and thyroiditis in rats
Although the MHC class II ‘u' haplotype is strongly associated with type 1 diabetes (T1D) in rats, the role of MHC class II in the development of tissue-specific autoimmune diseases including T1D and autoimmune thyroiditis remains unclear. To clarify this, we produced a congenic strain carrying...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308136/ https://www.ncbi.nlm.nih.gov/pubmed/21918539 http://dx.doi.org/10.1038/gene.2011.63 |