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Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells

BACKGROUND: Cryptococcus neoformans has a predilection for central nervous system infection. C. neoformans traversal of the blood brain barrier, composed of human brain microvascular endothelial cells (HBMEC), is the crucial step in brain infection. However, the molecular mechanism of the interactio...

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Detalles Bibliográficos
Autores principales: Long, Min, Huang, Sheng-He, Wu, Chun-Hua, Shackleford, Gregory M, Jong, Ambrose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308189/
https://www.ncbi.nlm.nih.gov/pubmed/22316086
http://dx.doi.org/10.1186/1423-0127-19-19