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A stochastic model of kinetochore–microtubule attachment accurately describes fission yeast chromosome segregation

In fission yeast, erroneous attachments of spindle microtubules to kinetochores are frequent in early mitosis. Most are corrected before anaphase onset by a mechanism involving the protein kinase Aurora B, which destabilizes kinetochore microtubules (ktMTs) in the absence of tension between sister c...

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Detalles Bibliográficos
Autores principales: Gay, Guillaume, Courtheoux, Thibault, Reyes, Céline, Tournier, Sylvie, Gachet, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308688/
https://www.ncbi.nlm.nih.gov/pubmed/22412019
http://dx.doi.org/10.1083/jcb.201107124