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A stochastic model of kinetochore–microtubule attachment accurately describes fission yeast chromosome segregation
In fission yeast, erroneous attachments of spindle microtubules to kinetochores are frequent in early mitosis. Most are corrected before anaphase onset by a mechanism involving the protein kinase Aurora B, which destabilizes kinetochore microtubules (ktMTs) in the absence of tension between sister c...
Autores principales: | Gay, Guillaume, Courtheoux, Thibault, Reyes, Céline, Tournier, Sylvie, Gachet, Yannick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308688/ https://www.ncbi.nlm.nih.gov/pubmed/22412019 http://dx.doi.org/10.1083/jcb.201107124 |
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