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A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning
During mitosis in budding yeast, cortically anchored dynein generates pulling forces on astral microtubules to position the mitotic spindle across the mother–bud neck. The attachment molecule Num1 is required for dynein anchoring at the cell membrane, but how Num1 assembles into stationary cortical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308694/ https://www.ncbi.nlm.nih.gov/pubmed/22431751 http://dx.doi.org/10.1083/jcb.201112017 |