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MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response
Stress in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), a multifaceted signaling system coordinating translational control and gene transcription to promote cellular adaptation and survival. Microribonucleic acids (RNAs; miRNAs), single-stranded RNAs that typically fun...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308703/ https://www.ncbi.nlm.nih.gov/pubmed/22431749 http://dx.doi.org/10.1083/jcb.201201077 |