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Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells

Niacin, also known as nicotinic acid, is an organic compound that has several cardio-beneficial effects. However, its use is limited due to the induction of a variable flushing response in most individuals. Flushing occurs from a niacin receptor mediated generation of prostaglandins from arachidonic...

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Detalles Bibliográficos
Autores principales: VanHorn, Justin, Altenburg, Jeffrey D, Harvey, Kevin A, Xu, Zhidong, Kovacs, Richard J, Siddiqui, Rafat A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308705/
https://www.ncbi.nlm.nih.gov/pubmed/22442634
http://dx.doi.org/10.2147/JIR.S29044