Mechanisms of Host Receptor Adaptation by Severe Acute Respiratory Syndrome Coronavirus

The severe acute respiratory syndrome coronavirus (SARS-CoV) from palm civets has twice evolved the capacity to infect humans by gaining binding affinity for human receptor angiotensin-converting enzyme 2 (ACE2). Numerous mutations have been identified in the receptor-binding domain (RBD) of differe...

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Detalles Bibliográficos
Autores principales: Wu, Kailang, Peng, Guiqing, Wilken, Matthew, Geraghty, Robert J., Li, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308800/
https://www.ncbi.nlm.nih.gov/pubmed/22291007
http://dx.doi.org/10.1074/jbc.M111.325803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308800/
https://www.ncbi.nlm.nih.gov/pubmed/22291007
http://dx.doi.org/10.1074/jbc.M111.325803

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