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Interactions of Cations with the Cytoplasmic Pores of Inward Rectifier K(+) Channels in the Closed State
Ion channels gate at membrane-embedded domains by changing their conformation along the ion conduction pathway. Inward rectifier K(+) (Kir) channels possess a unique extramembrane cytoplasmic domain that extends this pathway. However, the relevance and contribution of this domain to ion permeation r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308888/ https://www.ncbi.nlm.nih.gov/pubmed/21982822 http://dx.doi.org/10.1074/jbc.M111.278531 |