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Interactions of Cations with the Cytoplasmic Pores of Inward Rectifier K(+) Channels in the Closed State

Ion channels gate at membrane-embedded domains by changing their conformation along the ion conduction pathway. Inward rectifier K(+) (Kir) channels possess a unique extramembrane cytoplasmic domain that extends this pathway. However, the relevance and contribution of this domain to ion permeation r...

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Detalles Bibliográficos
Autores principales: Inanobe, Atsushi, Nakagawa, Atsushi, Kurachi, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308888/
https://www.ncbi.nlm.nih.gov/pubmed/21982822
http://dx.doi.org/10.1074/jbc.M111.278531