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Dominant Cross-Reactive B Cell Response during Secondary Acute Dengue Virus Infection in Humans

The four serotypes of dengue virus (DENV) cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Severe disease has been associated with heterotypic secondary DENV infection, mediated by cross-reactive antibodies (Abs) and/or cross-reactive T cells. The role of cross-r...

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Detalles Bibliográficos
Autores principales: Zompi, Simona, Montoya, Magelda, Pohl, Marie O., Balmaseda, Angel, Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308930/
https://www.ncbi.nlm.nih.gov/pubmed/22448292
http://dx.doi.org/10.1371/journal.pntd.0001568