Chemical Mechanism of UDP-Galactopyranose Mutase from Trypanosoma cruzi: A Potential Drug Target against Chagas' Disease

UDP-galactopyranose mutase (UGM) is a flavoenzyme that catalyzes the conversion of UDP-galactopyranose to UDP-galactofuranose, the precursor of galactofuranose (Galf). Galf is found in several pathogenic organisms, including the parasite Trypanosoma cruzi, the causative agent of Chagas' disease...

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Detalles Bibliográficos
Autores principales: Oppenheimer, Michelle, Valenciano, Ana Lisa, Kizjakina, Karina, Qi, Jun, Sobrado, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308961/
https://www.ncbi.nlm.nih.gov/pubmed/22448231
http://dx.doi.org/10.1371/journal.pone.0032918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308961/
https://www.ncbi.nlm.nih.gov/pubmed/22448231
http://dx.doi.org/10.1371/journal.pone.0032918

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