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A Sensitive and Quantitative Polymerase Chain Reaction-Based Cell Free In Vitro Non-Homologous End Joining Assay for Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are responsible for sustaining hematopoietic homeostasis and regeneration after injury for the entire lifespan of an organism. Maintenance of genomic stability is crucial for the preservation of HSCs, which depends on their efficient repair of DNA damage, particularly...

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Detalles Bibliográficos
Autores principales: Shao, Lijian, Feng, Wei, Lee, Kyung-Jong, Chen, Benjamin P. C., Zhou, Daohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308962/
https://www.ncbi.nlm.nih.gov/pubmed/22448248
http://dx.doi.org/10.1371/journal.pone.0033499