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Depleting Components of the THO Complex Causes Increased Telomere Length by Reducing the Expression of the Telomere-Associated Protein Rif1p

Telomere length is regulated mostly by proteins directly associated with telomeres. However, genome-wide analysis of Saccharomyces cerevisiae mutants has revealed that deletion of Hpr1p, a component of the THO complex, also affects telomere length. The THO complex comprises four protein subunits, na...

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Detalles Bibliográficos
Autores principales: Yu, Tai-Yuan, Wang, Chen-Yi, Lin, Jing-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308969/
https://www.ncbi.nlm.nih.gov/pubmed/22448247
http://dx.doi.org/10.1371/journal.pone.0033498