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Altered Trabecular Bone Structure and Delayed Cartilage Degeneration in the Knees of Collagen VI Null Mice

Mutation or loss of collagen VI has been linked to a variety of musculoskeletal abnormalities, particularly muscular dystrophies, tissue ossification and/or fibrosis, and hip osteoarthritis. However, the role of collagen VI in bone and cartilage structure and function in the knee is unknown. In this...

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Detalles Bibliográficos
Autores principales: Christensen, Susan E., Coles, Jeffrey M., Zelenski, Nicole A., Furman, Bridgette D., Leddy, Holly A., Zauscher, Stefan, Bonaldo, Paolo, Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308976/
https://www.ncbi.nlm.nih.gov/pubmed/22448243
http://dx.doi.org/10.1371/journal.pone.0033397