Disruption of Murine mp29/Syf2/Ntc31 Gene Results in Embryonic Lethality with Aberrant Checkpoint Response

Human p29 is a putative component of spliceosomes, but its role in pre-mRNA is elusive. By siRNA knockdown and stable overexpression, we demonstrated that human p29 is involved in DNA damage response and Fanconi anemia pathway in cultured cells. In this study, we generated p29 knockout mice (mp29(GT...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chia-Hsin, Chu, Po-Chen, Lee, Liekyeow, Lien, Huang-Wei, Lin, Tse-Ling, Fan, Chi-Chen, Chi, Peter, Huang, Chang-Jen, Chang, Mau-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308990/
https://www.ncbi.nlm.nih.gov/pubmed/22448250
http://dx.doi.org/10.1371/journal.pone.0033538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308990/
https://www.ncbi.nlm.nih.gov/pubmed/22448250
http://dx.doi.org/10.1371/journal.pone.0033538

Ejemplares similares