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Interaction between NANOS2 and the CCR4-NOT Deadenylation Complex Is Essential for Male Germ Cell Development in Mouse

Nanos is one of the evolutionarily conserved proteins implicated in germ cell development and we have previously shown that it interacts with the CCR4-NOT deadenylation complex leading to the suppression of specific RNAs. However, the molecular mechanism and physiological significance of this intera...

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Detalles Bibliográficos
Autores principales: Suzuki, Atsushi, Saba, Rie, Miyoshi, Kei, Morita, Yoshinori, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308992/
https://www.ncbi.nlm.nih.gov/pubmed/22448252
http://dx.doi.org/10.1371/journal.pone.0033558